Treatment of Primary Cutaneous Marginal Zone B-Cell Lymphomas with Intralesional Rituximab

Primary cutaneous marginal zone B-cell lymphoma.

Primary cutaneous marginal zone B-cell lymphoma (PCMZL) is included as one of the major types of primary cutaneous B-cell lymphoma in the revised World Health Organization-European Organization for Research and Treatment of Cancer classification. Clinically, PCMZL is an indolent disease and has an excellent prognosis. PCMZL is composed of a polymorphous infiltrate that includes centrocyte-like,...

[Cutaneous follicular center B-cell lymphoma treated with intralesional rituximab].

Cutaneous follicular center B-cell lymphomas are indolent tumors characterized by the presence of neoplastic follicular center cells. They contain a mixture of centrocytes with a variable number of centroblasts. The tumor is usually treated by surgery or radiotherapy, although other treatments may be used such as interferon-alpha, chemotherapy, and biological agents (rituximab). Rituximab is a ...

Intralesional Rituximab Treatment for Primary Cutaneous B-cell Lymphoma: Nine Finnish Cases.

Intralesional rituximab for cutaneous manifestations of systemic B-cell lymphoma

CBCL: cutaneous B-cell lymphoma INTRODUCTION Cutaneous B-cell lymphomas (CBCL) are a heterogeneous group of lymphoproliferative diseases that can be classified in 2 broad categories: primary and secondary. The latter implies a systemic lymphoproliferative disease that causes visible cutaneous lesions. Numerous articles regarding the diagnosis and treatment of primary CBCL have been published. H...

Nodal marginal zone B-cell lymphomas may arise from different subsets of marginal zone B lymphocytes.

Nodal marginal zone B-cell lymphoma (MZL) is a rare and not extensively studied entity that accounts for approximately 2% of all non-Hodgkin lymphomas. Complementarity-determining regions 2 and 3 (CDR2, CDR3) of the immunoglobulin heavy-chain variable region (V(H)) genes were amplified by polymerase chain reaction (PCR), cloned, and sequenced in 8 patients with nodal MZL. All showed a potential...